Retrospective significance of total bilirubin as a predictor of acute appendicitis

Résumé

Abstract Objective The present research aimed to examine the clinical importance of preoperative total bilirubinemia in patients with acute appendicitis and determine whether it has any practical application for predicting severe appendicitis. Methods A retrospective analysis of appendicectomies was done in one hospital (N = 636 cases of acute appendicitis presented to the emergency department between December 2019 and January 2023). Using multivariate analysis, we looked at predictive data for complex (perforated or gangrenous) appendicitis, including demographics, gender, white blood cell count, degree of C-reactive protein (CRP) elevation, high-temperature peritoneal signs and indicators, and total bilirubin level. Results Those with total bilirubin (>1.1 mg/dL), high CRP levels (>0.5 mg/dL), positive peritoneal irritated symptoms, and a temperature (>37.3 C) had considerably higher rates of acute appendicitis. Age (>64 years), hyperbilirubinemia, high CRP level, and fever (odds ratios of 3.36, 1.75, 7.61, and 2.43, respectively) were identified by multivariate analysis as associated risks for complex appendicitis. High temperatures, raised CRP levels, and hyperbilirubinemia were also found to be risks for complex appendicitis in all individuals, especially those under 65 years old (odds ratios: 1.99, 5.90, and 2.72, respectively). Conclusions High temperatures, elevated CRP, and high total bilirubin were good predictor factors of acute appendicitis, especially useful among cases younger than 65 years, but total bilirubin was a more precise indicator.

Citer ce document

Accès au document

Texte intégral en lecture en ligne, réservé aux abonnés SPHAERO et aux membres de l'institution. Se connecter

Auteur(s)

Statistiques

Consultations : 1

Téléchargements : 0