Effect of XP-endo Finisher and EDDY activation on post-operative pain after single-visit endodontic treatment: a randomized controlled clinical trial

Résumé

Advanced irrigation techniques, such as the XP-endo Finisher file and sonic EDDY system, have been introduced to overcome the limitations of conventional needle irrigation by enhancing irrigant penetration and disinfection. However, their influence on post-operative pain remains under investigation. This study aimed to evaluate the effect of these techniques on post-operative pain following single-visit root canal treatment. Thirty patients requiring endodontic treatment for asymptomatic vital maxillary central incisors or canines were enrolled. All procedures were performed in a single visit using the ProTaper Universal rotary system. Irrigation was carried out with 2.5% sodium hypochlorite (NaOCl). Participants were randomly assigned into three equal groups based on the final irrigation protocol: Group I - conventional needle irrigation (control), Group II - XP-endo Finisher file, and Group III - sonic EDDY activation. Post-operative pain was assessed using a Visual Analogue Scale (VAS) at 8, 24, and 48 h, and at 1 and 2 weeks. Data were statistically analyzed with significance set at P ≤ 0.05. Pain scores significantly decreased overtime in all groups. While between-group differences were not statistically significant, within-group reductions were significant. Group II exhibited the lowest pain levels, followed by Group III, while Group I reported the highest. Additionally, female participants had significantly higher odds of reporting pain. The XP-endo Finisher and sonic EDDY systems resulted in better pain reduction over time than conventional needle irrigation, with XP-endo Finisher being most effective. CLINICAL RELEVANCE: Advanced irrigation systems may enhance patient comfort and compliance by reducing post-operative pain after endodontic therapy. CLINICAL TRIAL REGISTRATION: The study protocol was registered on https://beta. CLINICALTRIALS: gov identifier: NCT05450003 on (08/07/2022).

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