Seroprevalence of Hepatitis B, Hepatitis C, and HIV in pregnant women attending a tertiary care hospital in Mogadishu, Somalia, 2017-2021

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Abstract Hepatitis B, C, and HIV infections are serious global health concerns, affecting both developed and developing nations. This study reported from Somalia that determines the prevalence of hepatitis B, hepatitis C, and HIV among pregnant women attending a tertiary hospital in Mogadishu, Somalia. Pregnant women with missing variables, who had a history of liver disease, diabetes, and HELLP syndrome were excluded. HBsAg, anti-HCV, and Anti HIV were measured using Enzyme-Linked Immunosorbent Assay in the hospital’s biochemistry laboratory. Over a 5-year period, hepatitis B, C, and HIV infections were requested from 7874 pregnant mothers. 7836 were tested for hepatitis B infection, with 220 (2.8%) having HBsAg positivity. 7791 pregnant women were tested anti-HCV, with 33 (0.4%) having anti-HCV seropositivity and 7854 pregnant women were tested for HIV, with 16 (0.2%) positive. This study shows that the HBV prevalence in pregnant women is 2.8%, which is lower than previous reports. HCV in pregnant women is the first study reported in the country. HIV infection also indicates a high prevalence among pregnant women in Somalia. Antenatal screening for these infections is recommended, as there are critical therapies available for both the mother and newborn.

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