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Assessment of the Acute Phase Response in Healthy and Injured Southern White Rhinoceros (Ceratotherium simum simum)

Article scientifique 2020 Anglais

Résumé

= 30) were compared. Diagnostic performance was evaluated using receiver-operator characteristic (ROC) curve and logistic regression analyses. RIs were: albumin 18-31 g/L, fibrinogen 1.7-2.9 g/L, haptoglobin 1.0-4.3 g/L, iron 9.7-35.0 μmol/L, SAA <20 mg/L. Iron and albumin were lower and fibrinogen, haptoglobin and SAA higher in injured vs. healthy animals. Iron showed the best diagnostic accuracy followed by fibrinogen, albumin, haptoglobin and SAA. Iron ≤ 15.1 μmol/L and haptoglobin >4.7 g/L were significant predictors of inflammatory status and together correctly predicted the clinical status of 91% of cases. SAA > 20 mg/L had a specificity of 100%. In conclusion, albumin and iron are negative and fibrinogen, haptoglobin and SAA positive APRs in the white rhinoceros. The combination of iron and haptoglobin had an excellent diagnostic accuracy for detecting inflammation.

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Hooijberg, E., Cray, C., Steenkamp, G., Buss, P., Goddard, A., Miller, M. (2020). Assessment of the Acute Phase Response in Healthy and Injured Southern White Rhinoceros (Ceratotherium simum simum). https://doi.org/10.3389/fvets.2019.00475

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Auteur(s)

Emma H. Hooijberg Carolyn Cray Gerhard Steenkamp Peter Buss Amelia Goddard Michele A. Miller

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