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Meary Angle for the prediction of mitral valve prolapse risk in non-syndromic patients with pes planus, a cross-sectional study

Article scientifique 2022 Anglais

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Abstract Objectives: Mitral Valve prolapse (MVP) is the commonest valvular abnormality. There is a reported association between pes planus (PP) and MVP in some syndromes such as Marfan, however, this association has not been tested in non-syndromic cases. The primary outcome of this study is to measure the prevalence of MVP in a population of patients with PP. The secondary outcome parameter is to determine if the Meary angle (MA), a measure of severity of flat foot, can be effectively used in the prediction of the presence of MVP. Forty-One patients with PP have been screened with lateral x-ray foot to determine MA and echocardiography to determine the presence and grade of MVP.Results: 88% of screened patients were diagnosed with MVP. MA was correlated with the grade of MVP and showed high diagnostic accuracy (Sensitivity 100% and Specificity 90%) in predicting MVP risk when higher than 5. Children with PP are at a higher risk of MVP than the general population. Utilizing MA in such a specific population for the determination of patients at the higher need for echocardiography seems to be a useful strategy to diagnose MVP in those patients.

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AbdelMassih, A., Hozaien, R., Mishriky, F., Michael, M., AmanAllah, M., Ali, N., Elgamal, N., Medhat, O., Kamel, M., Helmy, R., Sarhan, M., Attalla, H., Dawoud, O., Marwan, A., Ghobashy, M. (2022). Meary Angle for the prediction of mitral valve prolapse risk in non-syndromic patients with pes planus, a cross-sectional study. https://doi.org/10.21203/rs.3.rs-1352778/v1

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