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Karyomegalic interstitial nephritis as a rare cause of kidney graft dysfunction: case report and review of literature

Article scientifique 2023 Anglais

Résumé

Karyomegalic interstitial nephritis (KIN) is a rare cause of chronic interstitial nephritis characterized by enlarged renal tubular epithelial nuclei. The first case of KIN reported in a kidney graft was in 2019. Here, we report the first case of KIN in 2 brothers receiving kidneys from 2 different unrelated living donors. A male kidney transplant recipient with focal segmental glomerulosclerosis as the original kidney disease presented with graft impairment and proteinuria, and graft biopsy revealed KIN. This patient had a brother who was also a kidney transplant recipient and had one episode of graft impairment and was diagnosed with KIN as well.

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Moustafa, F., Nagy, E., Elwasif, S., Sobh, M. (2023). Karyomegalic interstitial nephritis as a rare cause of kidney graft dysfunction: case report and review of literature. https://doi.org/10.1186/s12882-023-03185-3

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Auteur(s)

Fatma El-Husseiny Moustafa Eman Nagy Salwa Mahmoud Elwasif Mohamed Sobh

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