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Adverse childhood experiences and disengagement from HIV care: a case-cohort study in Tanzania

Article scientifique 2025 Anglais

Résumé

Abstract Adverse childhood experiences (ACEs) can have lasting, detrimental effects throughout the lifespan and may influence engagement in health care. We conducted a case-cohort study in Tanzania to estimate the association between ACEs and disengagement from HIV care 12 months after initiating antiretroviral therapy (ART) among 217 adults (26 cases and 191 sub-cohort participants). Experiencing one, two, three, and four additional ACEs was significantly associated with 28% (RR a = 1.24; 95% CI: 1.05, 1.44; p -value < 0.01), 64% (RR a =1.64; 95% CI: 1.22, 2.20), 110% (RR a =2.10; 95% CI: 1.35, 3.26), and 168% (RR a =2.68; 95% CI: 1.49, 4.38) increases in the risk of disengagement from HIV care, respectively. These findings call for integrated trauma-informed mental health services within HIV care to end HIV/AIDS as a public health threat.

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Tucker, S., Winters, S., Katabaro, E., Mlowe, M., Bradshaw, P., Ahern, J., Colford, J., Packel, L., Hillis, S., Sabasaba, A., Njau, P., McCoy, S. (2025). Adverse childhood experiences and disengagement from HIV care: a case-cohort study in Tanzania. https://doi.org/10.1186/s12981-025-00760-6

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Auteur(s)

Sydney Tucker Solis Winters Emmanuel Katabaro Matilda Mlowe Patrick T. Bradshaw Jennifer Ahern John M. Colford Laura Packel Susan D. Hillis Amon Sabasaba Prosper Njau Sandra I. McCoy

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