Determinants of Mother to Child HIV Transmission (HIV MTCT); A Case Control Study in Governmental Health Centers of East Gojjam Zone, Northwest Ethiopia, 2019

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Abstract Background: Mother to child human immune virus (HIV) transmission is the passage of HIV from mother to her child during pregnancy, labor, delivery or breast-feeding. The objective of this study was to identify determinants of mother to child HIV transmission in Governmental health centers of East Gojjam Zone, Northwestern Ethiopia, 2019. Methods: A case control study was conducted on 210(42 cases and 168 controls). All cases were included in the study. Controls were selected by simple random sampling. Secondary data were collected from April 1 to 30/2019. Collected data were entered by using epi data version 3.1 and then it was exported to SPSS. The exported data was analyzed and presented by using descriptive summary statistics and tables. After bivariate logistic regression analysis, all variables with p-value 0.25 were entered into multivariable logistic regression and p value < 0.05 considered as significantly associated with the outcome variable.Results: Having history of antenatal care follow up of HIV positive pregnant women [ adjusted odds ratio (AOR)=5.0;95%CI; 2.02-12.16] and initial CD4 count of mothers [AOR=2.7;95%CI;1.35-5.52]. Conclusion: Mother to child HIV transmission was significantly associated with history of ANC follow up of mothers and initial CD4 counts of mothers.

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