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Low levels of systemic inflammation in asymptomatic TB detected during community-based screening in rural South Africa

Article scientifique 2025 Autre

Résumé

ABSTRACT Asymptomatic TB represents half of prevalent TB yet frequently remains undetected. We assessed the performance of plasma IL-6 and CRP as diagnostic biomarkers for asymptomatic TB identified by community-based screening. Both proteins were elevated in asymptomatic TB compared to community controls, but neither performed well as a diagnostic biomarker.

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Mtshali, L., Olivier, S., Fehr, J., Zulu, T., Gareta, D., Baisley, K., Hanekom, W., Ndung’u, T., Leslie, A., Wong, E. (2025). Low levels of systemic inflammation in asymptomatic TB detected during community-based screening in rural South Africa. https://doi.org/10.64898/2025.12.10.25341906

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Auteur(s)

Lerato Noluthando Mtshali Stephen Olivier Jana Fehr Thando Zulu Dickman Gareta Kathy Baisley Willem A. Hanekom Thumbi Ndung’u Alasdair Leslie Emily Wong

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