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Performance evaluation of three rapid screening assays for detection of antibodies to hepatitis C virus in Cameroon

Article scientifique 2018 Anglais

Résumé

This study was aimed at evaluating the performance of three CE-marked rapid diagnostic tests (RDTs): Multisure-HCV, First Response ® and Toyo ® ; for screening anti- HCV antibody using plasma samples. Overall, 200 plasma samples were used. Sensibility and specificity of these RDTs range from 71 to 99 and 78 to 100% respectively. Multisure scored a sensitivity at 99% (95% CI 97–100%) and First Response reached a specificity at 90% (95% CI 85–94.9%). Further studies should be conducted to establish an algorithm using these RTDs for the detection of HCV infection in Cameroon.

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Fondjo, C., Tagnouokam‐Ngoupo, P., Ngono, L., Plantier, J., Njouom, R. (2018). Performance evaluation of three rapid screening assays for detection of antibodies to hepatitis C virus in Cameroon. https://doi.org/10.1186/s13104-018-3465-8

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Auteur(s)

Clavel Landry Kouam Fondjo Paul Alain Tagnouokam‐Ngoupo Laure Ngono Jean‐Christophe Plantier Richard Njouom

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