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Frequency of IDH1 mutation in adult-type diffuse astrocytic gliomas in a tertiary hospital in Kenya

Article scientifique 2024 Anglais

Résumé

The 2021 WHO classification of gliomas has separated gliomas based on their IDH mutation status, reflecting differences in their pathogenesis and clinical characteristics. There is a paucity of data on the prevalence of IDH mutations in gliomas in this region. This study aimed to determine the frequency of the IDH1 mutation in adult-type diffuse astrocytic gliomas in a tertiary hospital in Kenya. Approximately half of the gliomas were positive for the IDH1 mutation, with a slight male predominance. Our study provides crucial insights into the frequency of IDH1 mutations in gliomas in Kenya.

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Gakinya, S., Mutuiri, A., Onyuma, T., Cheserem, B., Mogere, E. (2024). Frequency of IDH1 mutation in adult-type diffuse astrocytic gliomas in a tertiary hospital in Kenya. https://doi.org/10.3389/fmed.2024.1305714

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Auteur(s)

Samuel Gakinya Anderson Mutuiri Timothy Onyuma Beverly Cheserem Edwin Mogere

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