Correlation between Vitamin D Level and the Development of Idiopathic Scoliosis in Pediatric Population: Early Detection

Résumé

Abstract Background Adolescent idiopathic scoliosis (AIS) is the most common spinal deformity with unclear etiology. Vitamin D deficiency may contribute to the etiology of AIS through its impacts on bone metabolism. The aim of this study is to examine the correlation between vitamin D level and the development of idiopathic scoliosis in pediatric patient. Methods This study involved 130 patients diagnosed with idiopathic scoliosis aged 7 to 18 years at a physiotherapy and rehabilitation center, Qena, Egypt, between May 2021 and October 2022. Patients’ clinical and demographic data were extracted from the medical record including age, gender, height, weight, serum vitamin D level, and Cobb angle. Scoliosis was identified when Cobb angle equal to and greater than 10 degrees. Results Patients’ mean age was 13.1 ± 2.75 years, mean level of vitamin D in the sample was 10.3 ng/ml ± 4.76, mean weight of 47.4 kg ± 9.63. In the patient group, the mean value of the Cobb angle was 16.8 degrees 5.79 with a 95% CI between 15.8 and 17.8. Vitamin D level was positively correlated with age (p < 0.001, r = 0.45), Cobb angle (p = 0.18, r = 0.11), and weight (p < .001, r = 0.51), Conclusion In conclusion, we found that vitamin D deficiency may contribute to the pathogenesis of AIS by affecting the metabolism of calcium and phosphorus in human bone. As a result, we recommended testing vitamin D levels in those with AIS. there is a positive correlation between vitamin D levels and Cobb's angle. Vitamin D deficiency/insufficiency should be examined in patients having AIS.

Citer ce document

Accès au document

Texte intégral en lecture en ligne, réservé aux abonnés SPHAERO et aux membres de l'institution. Se connecter

Auteur(s)

Statistiques

Consultations : 1

Téléchargements : 0