Prevalence, Antimicrobial Susceptibility Pattern, And Associated Factors of Urinary Tract Infections Among Diabetic Patients at Dongla State, Sudan

Résumé

fever, chills, dysuria, urinary urgency, frequency and cloudy or malodorous urine.Infections are almost always ascending in origin and caused by bacteria in the periurethral flora and the distal urethra.These bacteria inhabit the distal gastrointestinal tract and colonize the perineal area.E. coli usually causes a child's first infection [4] but other gram-negative bacilli and Enterococci may also cause infection.Staphylococcal infections, especially those due to Staphylococcus saprophyticus are common causes of urinary tract infection among female adolescents.Diabetes Mellitus (DM) is a group of metabolic disorder characterized by hyperglycemia resulting from defects in insulin secretion, insulin Abstract Urinary tract infections are the most common bacterial infections in humans.UTI causes considerable morbidity in diabetic patients and if complicated, can cause severe renal damage and life threatening infections.The present study was aimed to determine the Prevalence, Antimicrobial Susceptibility Pattern, and Associated Factors of Urinary Tract Infections among Diabetic Patients.A cross-sectional study was conducted during the period from August 2019 to April 2020.Data were collected using structured questionnaire.Clean-catch, midstream urine samples were collected and cultured for UTI diagnosis and antimicrobial susceptibility.significant bacteriuria was defined as a positive urine culture (≥105 colony-forming units).The predominant isolates were Escherichia coli (60%), K. pneumoniae (15%), P. aeruginosa (8%), E. feacalis (6.5%), P. mirabilis (1%), S, aureus (2.5%) and C. albicans (7%).Antimicrobial Susceptibility Pattern of Gram-negative bacteria were showed sensitive to colistin (99%), meropenem (95%), and gentamycin (48%), but were resistant to cefpodoxime (99%) and ciprofloxacin (65%).Grampositive bacteria isolates showed a higher level of sensitivity to colistin (100%), meropenem (80%), followed by ciprofloxacin, ceftriaxone and gentamycin (60%).Isolation of uropathogenic bacteria and antimicrobial susceptibility testing are crucial for the treatment of UTI in diabetic patients.Resistance rates among common uropathogens continue to evolve and appear to be increasing too many commonly used antimicrobial agents and a continued surveillance of resistance rates among uropathogens is needed to controlling this global problem.

Citer ce document

Accès au document

Ce document est hébergé sur son dépôt institutionnel d'origine.

Auteur(s)

Statistiques

Consultations : 1

Téléchargements : 0