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Peer Review Report For: Case Report: An unusual case of severe autoimmune hemolytic anemia in untreated hepatitis C viral infection [version 1; peer review: 1 approved, 1 approved with reservations]

Article scientifique 2024 Anglais

Résumé

Patients with hepatitis C share a variety of anemia, including bleeding, nutritional deficiencies, and anemia of chronic disease. Autoimmune hemolytic anemia (AIHA) is usually reported with interferon-alpha and/or ribavirin treatment in hepatitis C virus (HCV) infections. We report an unusual case of AIHA occurring in a49-year-old patient with untreated hepatitis C infection who presented with functional anemia syndrome. Monospecific direct antiglobulin test showed the presence of anti-complement (C3d++). Cold agglutinin titer was 1/16 at 4°C. The patient improved following blood transfusion, steroid therapy and direct acting antivirals.

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Debbabi, H., Chakroun, A., Elloumi, H., Yacoub, H., Azouz, S., Marouani, R. (2024). Peer Review Report For: Case Report: An unusual case of severe autoimmune hemolytic anemia in untreated hepatitis C viral infection [version 1; peer review: 1 approved, 1 approved with reservations]. https://doi.org/10.5256/f1000research.162939.r324838

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Auteur(s)

Habiba Debbabi A Chakroun H Elloumi H Yacoub S Ben Azouz R Marouani

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