Phytochemicals, Total Phenolic and Flavonoid Contents and Radical Scavenging Activities of Crotalaria Retusa, Clerodendrum Volubile Leaf Extracts and Biogas Slurry of Cassava Peels

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Abstract Well established are the destructive effects of cellular oxidative damage due to oxidative stress on animal and human health. The prophylactic use of plant-derived bioactive agents in the amelioration and treatment of chronic diseases induced by free radical and oxidative stress is a promising therapeutic approach. This present study investigates the phytochemical constituents, in vitro antioxidant and free radical scavenging abilities of Crotalaria retusa leaves, Clerodendrum volubile leaves and cassava biogas slurry. The total phenolic and flavonoid contents of the extracts were also determined. The phytochemicals, phenolic and flavonoid contents and antioxidant potentials of the extracts, including reducing power, inhibition of hydrogen peroxide, hydroxyl radical production, and DPPH radical scavenging, were performed using standard assays. Our results show terpenoids, saponins, cardiac glycosides, flavonoids and tannins in the various extracts. In vitro, antioxidant assay results also reveal that the extracts' free radical scavenging abilities are significantly high compared with standard antioxidants used: tannic and ascorbic acids. The results also show that the extracts demonstrated elevated antioxidant activities positively correlated with the total flavonoid and phenolic contents. This work demonstrated that the extracts possessed significant antioxidant activities over standard ones, thus, suggesting the extracts as sources of natural antioxidants that could have considerable therapeutic relevance in preventing and inhibiting the progression of diseases associated with oxidative stress.

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