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Polycythemia Vera: Current Therapeutic Approaches
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The hemoglobin level threshold required to diagnose PV is now established at 16.5 g/dL for men and 16 g/dL for women by the 2016 WHO classification for MPNs. The clinical course of PV might be interrupted by thrombohemorrhagic complications and disease transformation to MF or acute myeloid leukemia. JAK2 oncogenes homozygosity may result in distinct tumorigenic consequences. Different therapeutic strategies and good candidates' patients for such therapies are illustrated.
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Hamed, N.
(2018). Polycythemia Vera: Current Therapeutic Approaches.
https://doi.org/10.19080/jtmp.2018.03.555620
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