Beyond neurons: astrocytic ensembles stabilize memories after recall

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In a recent study published in Nature , Dewa et al. showed that emotionally salient experiences “biologically tag” small ensembles of astrocytes, creating multiday traces that can be reactivated during recall. 1 This mechanism reveals a previously unrecognized astrocytic contribution to the stabilization of recalled memories and expands the traditional neuron-centric model of memory storage, offering insights that may inform future strategies for modulating memory in cognitive and neuropsychiatric disorders. 1

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