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Ecofriendly biosynthesis of Ag-NPs by Streptomyces griseus eradicating Candida albicans associated with different types of dysspermatism

Article scientifique 2022 Anglais

Résumé

Abstract Silver nanoparticles Ag-NPs have potent biological properties such as antibacterial, antifungal, anti-viral and anti-inflammatory activities. A simple, eco-friendly, inexpensive method was conducted in order to synthesize silver nanoparticles by actinomycetes. A total of 17 actinomycetes isolates were recovered from serially diluted compost sample and subsequently examined for their capabilities to produce Ag-NPs. Alongside, Candida albicans was isolated from human semen that affect male infertility, and subsequently submitted to susceptibility test using the well diffusion method. It was found that the Ag-NPs biosynthesized by Streptomyces griseus Azhar.S2 have high zone of inhibition against Candida albicans which was recorded by measuring the diameter of inhibition zone that was 20.5 ± .05 mm. The biosynthesized Ag-NPs had been characterized using UV-vis spectroscopy, FTIR, EDX and TEM. Conclusively, Candida albicans isolated from different types of dysspermatism human semen was highly eradicated by microbially synthesized Ag-NPs from Streptomyces griseus Azhar.S2.

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El-Enain, I., Abed, N., Helal, E., Abdelkhalek, E., Suleiman, W. (2022). Ecofriendly biosynthesis of Ag-NPs by Streptomyces griseus eradicating Candida albicans associated with different types of dysspermatism. https://doi.org/10.21203/rs.3.rs-1730237/v1

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Auteur(s)

Inas M. Abou El-Enain Nermine N. Abed Eman El-Husseiny Helal Eman S. Abdelkhalek Waleed B. Suleiman

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