Accès ouvert

Evaluation of total oxidative stress and antioxidant capacity of brain tumour patients attending referral hospitals in Addis Ababa, 2020: a comparative cross-sectional study

Article scientifique 2022 Anglais

Résumé

Background: The exact cause of brain tumours is still unknown, but disruptions of redox balance are thought to play a significant role in all stages of brain tumour development. However, the roles of free radical imbalance at different grades of brain tumour and degree of oxidative stress before and after surgery have not been addressed in prior studies. Aim: A comparative cross-sectional study was conducted to assess the redox imbalance among confirmed brain tumour patients. Methods and results: ≤ 0 05). Conclusion: Higher oxidant and lower antioxidant levels were found in the serum of brain tumour patients than in the control group. The post-surgery oxidant level was lower than the pre-surgery state. The findings of this study could suggest that redox imbalance may have a role in the pathophysiology of brain tumours, but further experimental studies are needed.

Citer ce document

Admasu, F., Demissie, B., Yitbarek, G., Geto, Z., Tesfaw, A., Zewde, E., Tilahun, A., Ayehu, G., Bekele, T., Habte, M., Feyisa, T., Amare, T., Bayih, W., Asnakew, S., Sisay, E., Tiruneh, M., Yemata, G., Aytenew, T., Dejenie, T. (2022). Evaluation of total oxidative stress and antioxidant capacity of brain tumour patients attending referral hospitals in Addis Ababa, 2020: a comparative cross-sectional study. https://doi.org/10.3332/ecancer.2022.1391

Accès au document

Voir sur le dépôt source

Ce document est hébergé sur son dépôt institutionnel d'origine.

Auteur(s)

Fitalew Tadele Admasu Biruk Demissie Getachew Yideg Yitbarek Zeleke Geto Aragaw Tesfaw Edget Abebe Zewde Animut Tilahun Gashaw Walle Ayehu Tigist Tefera Bekele Mezgebu Legesse Habte Teka Obsa Feyisa Tadeg Jemere Amare Wubet Alebachew Bayih Sintayehu Asnakew Ermiyas Sisay Markeshaw Tiruneh Getaneh Atikilt Yemata Tigabu Munye Aytenew Tadesse Asmamaw Dejenie

Statistiques

Consultations : 1

Téléchargements : 0