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APPORT DE LA CYTOPONCTION GANGLIONNAIRE DANS LE DIAGNOSTIC DES ADENOPATHIES TUMORALES.

Thèse 2018 Français

Résumé

lymph nods enlargement are a frequent reason for consultation that require a rigorous assessment, complete and fast. Fine needle aspiration cytology is currently the procedure of choice for orienting the diagnosis. Objectives o: To evaluate the accuracy of fine needle aspiration in the management of malignant lymph nods enlargement Methods: This was a retrospective study that analyzed 44 fine needle aspiration collected at the laboratory of pathology of the Farhat Hached University Hospital of Sousse over a period of 10 years (January 2007 - December 2017). Results: The mean age at the time of cytopunction was 37 years, with a sex ratio of 1.58. Results of cytology were inconclusive in 4 patients, the 40 conclusive results were divided into 3 cases negative, 4 suspect cases and 33 malignant cases. The malignant cytologies are divided into 12 metastases and 21 lymphomas, of which 47.6% are HML, 33.3% are large cell HML, 4.8% are small cell HML and for the rest (14.3%) there was no typing. The cytology in favor of metastasis were divided in papillary thyroid carcinoma (25%), mammary adenocarcinoma (16.7%), UCNT (50%) and one only case of squamous cell carcinoma (8.3%). The study of the concordance between the cytological data and the histological results had shown an Kappa index of 0.89 for lymphomas and a Kappa index of 0.65 for carcinomas, with a Kappa index of 0.89 for lymphomas and a Kappa index of 0.65 for carcinomas, with a Kappa index of 0.89 for lymphomas and a Kappa index of 0.65 for carcinomas. 0.76, in fact, in 32 cases the cytology results are consistent with the histology results. However, a discrepancy was noted in 8 cases. The sensitivity of the cytopunction was 95.2% for the lymphomas and 75.1% for metastases with an overall sensitivity of 84.1%. Conclusion: Our results are in agreement with those of the literature, fine needle aspiration cytology is a high-performance diagnostic test for malignant adenopathy.

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Bdioui, A., Médecine, F., Raies, R. (2018). APPORT DE LA CYTOPONCTION GANGLIONNAIRE DANS LE DIAGNOSTIC DES ADENOPATHIES TUMORALES..

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