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Management of patients with acute ST-elevation myocardial infarction: Results of the FAST-MI Tunisia Registry

Article scientifique 2019 Anglais

Résumé

BACKGROUND: The FAST-MI Tunisia registry was set up by the Tunisian Society of Cardiology and Cardiovascular Surgery to assess the demographic and clinical characteristics, management and hospital outcome of patients with ST-elevation myocardial infarction (STEMI). METHODS: Data for 459 consecutive patients (mean age 60.8 years; 88.5% male) with STEMI, treated in 16 public hospitals (representing 72.2% of public hospitals in Tunisia treating STEMI patients), were collected prospectively.The most common risk factors were smoking (63.6%), hypertension (39.7%), diabetes (32%) and dyslipidaemia (18.2%). RESULTS: Among the 459 patients, 61.8% received reperfusion therapy: 30% with primary percutaneous coronary intervention (PPCI) and 31.8% with intravenous fibrinolysis (IF) (28.6% with pre-hospital thrombolysis). The median time from symptom onset to thrombolysis was 185 min and to PPCI was 358 min. In-hospital mortality was 5.3%. Compared with those managed at regional hospitals, patients managed at interventional university hospitals (n = 357) were more likely to receive reperfusion therapy (52.9% vs. 34.1%; p<0.001), with less IF (28.6% vs. 43.1%; p = 0.002) but more PPCI (37.8% vs. 3.9%; p<0.0001). However, in-hospital mortality in the two types of hospitals was similar (5.3% vs. 5.1%; p = 0.866). CONCLUSIONS: Data from the FAST-MI Tunisia registry show that a pharmaco-invasive strategy of management for STEMI should be promoted in non-interventional regional hospitals.

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Addad, F., Mahdhaoui, A., Jeridi, G., Boughzéla, E., Kamoun, S., Boujnah, M., Haouala, H., Gamra, H., Maatouk, F., Khalfallah, A., Kachboura, S., Baccar, H., Halima, N., Guesmi, A., Sayahi, K., Sdiri, W., Neji, A., Bouakez, A., Milouchi, S., Battikh, K., Jullières, Y., Danchin, N., Monsuez, J., Mulak, G., Hagège, A., Bataille, V., Chettaoui, R., Mourali, M. (2019). Management of patients with acute ST-elevation myocardial infarction: Results of the FAST-MI Tunisia Registry. https://doi.org/10.1371/journal.pone.0207979

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