Associations between iron status and psychosocial well-being among pregnant women in Cape Coast, Ghana: a longitudinal study

Résumé

Abstract Objective: To determine the associations among Fe status, depressive/anxiety symptoms and quality of life (QoL) throughout pregnancy. Design: This longitudinal study recruited participants in their first trimester (< 13 weeks; n 116) and followed in their second ( n 71) and third ( n 71) trimesters. Socio-demographic, food security, anxiety, depressive symptoms and QoL questions were collected. Hb, ferritin (Ft) and transferrin saturation (TSAT) were determined. Women were categorised as iron improvers or non-improvers based on changes in Fe status. Associations were assessed using difference-in-difference analyses. Setting: Cape Coast, Ghana between October 2017 and September 2018. Participants: Pregnant women, 18–38 years. Results: Improvement in Ft levels from the first to second trimester was associated with reduced depressive symptoms (–2·96 v . –0·58, P = 0·028) and higher overall QoL (13·99 v . 1·92, P = 0·006) particularly role physical (23·32 v . –2·55, P = 0·025) and role emotional (27·50 v . 10·06, P = 0·025) subscales. Improvement in Hb levels during the same period was linked to less anxiety, particularly fear factor (–2·62 v . –0·51, P = 0·020), and worsened physical health aspect of QoL (–21·80 v . –3·75, P = 0·005). Improvement in TSAT levels from second to third trimester was associated with increased total anxiety (1·56 v . –0·64, P = 0·030) and panic factor (0·45 v . –0·26, P = 0·004) and decreased total QoL (–1·08 v . 7·94, P = 0·017), specifically role physical (–10·98 v . 11·93, P = 0·018). Conclusion: Increases in Fe status from first to second trimester were related to improvements in psychosocial well-being, implying potential benefit of Fe supplementation on affect in early pregnancy. Larger studies are needed to confirm these findings.

Citer ce document

Accès au document

Texte intégral en lecture en ligne, réservé aux abonnés SPHAERO et aux membres de l'institution. Se connecter

Auteur(s)

Statistiques

Consultations : 1

Téléchargements : 0