Weight Management Merits Attention in women with infertility: A Cross-Sectional Study on the Association of Anthropometric Indices with Hormonal Imbalance in a Ghanaian Population

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Abstract Objective This study determined the association of anthropometric indices with hormonal imbalance among infertile women in a Ghanaian population. Results Follicle stimulating hormone (FSH) levels (18.47 vs 8.67, p-value =0.002), and luteinisation hormone (LH) (12.43 vs 8.01, p-value =0.044) were higher in women with primary infertility compared to women presenting with secondary infertility. WC and WHtR showed significant negative partial correlation with prolactin in both primary and secondary infertile women. Also a significant negative partial correlation was observed between BMI and prolactin in secondary fertility only. WHR showed a positive association with LH in both primary and secondary infertility. WHR also showed significant positive correlation to LH/FSH ratio in secondary infertility whereas BAI showed a negative correlation to LH/FSH ratio. In a correlation analysis of anthropometric measures with hormonal profile and aetiology of infertility as a fixed factor indicated that the association between anthropometric indices and fertility hormones is largely dependent on the aetiology of infertility.

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