Comparison of the remineralization effectiveness of three remineralizing agents on artificial enamel lesions: an in vitro study

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INTRODUCTION: Early enamel demineralization can be reversed through remineralization, which restores lost minerals to strengthen enamel and prevent decay. AIM: This study evaluated the remineralization efficiency of three commercial treatments on artificially demineralized primary enamel. METHODS: Forty exfoliated primary anterior teeth were demineralized and divided into five groups: untreated control, artificial saliva, fluoridated toothpaste, Curasept toothpaste, and BioMin toothpaste. The treatments were applied for 28 days. Remineralization efficacy was assessed using Vickers microhardness testing, surface roughness measurement, and Scanning electron microscope combined with EDX (SEM-EDX). One-way ANOVA and Tukey's HSD test were used for statistical analysis. RESULTS: Microhardness and surface roughness tests confirmed BioMin's superior remineralization potential. Scanning electron microscopy showed that untreated enamel exhibited extensive demineralization, whereas treated groups displayed varying degrees of remineralization. BioMin demonstrated the highest calcium, phosphate, and fluoride incorporation, followed by Curasept and fluoridated toothpaste. The artificial saliva group showed no significant improvement over the control. CONCLUSION: BioMin, followed by Curasept and fluoridated toothpaste, effectively remineralized demineralized enamel. BioMin's bioactive glass formulation provided the highest mineral gain, suggesting its potential for non-invasive enamel restoration in pediatric dentistry.

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