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The Efficacy of Low-Intensity Shock Wave Therapy based on the Stratification of Erectile Dysfunction Patients: A Long-term Follow-up

Article scientifique 2023 Anglais

Résumé

Abstract Objectives Low intensity extracorporeal shockwave therapy (LIESWT) significantly improves erectile function in patients with vasculogenic erectile dysfunction (ED). We aimed to evaluate the effect of LI-ESWT on different subtypes of ED and to assess through a long-term follow up how long the improvement in erectile function lasts.Methods This was a retrospective review of a prospectively maintained database at the department of urology at Cairo university hospitals. Patients with vasculogenic ED underwent 6–12 sessions of focal LI-ESWT 5000 impulses 0.01 j/mm2 using the electromagnetic Dornier Aries® 1 machine. All patients received at least 6 sessions of LI-ESWT. Then, patients were assessed clinically by using the erection hardness scores (EHS), and erectile function using the international index of erectile function (IIEF-EF) domain score at three months post LI-ESWT and every six months. Also, penile hemodynamics at three months post LI-ESWT and at the last follow up visit.Results 42 patients were identified with mean age 50 ± 12 years, mean ED duration 31 ± 35 months and mean follow up 10 ± 6 months. Overall IIEF-EF was 16 ± 6 and improved to 22 ± 6 at three months and to 21 ± 6 at last follow up (p < 0.01). Minimally important clinical difference was achieved in 69% at three months and in 60% of the whole cohort at last follow up. Risk factors associated with higher MICD at three months were age (p = 0.01), uncontrolled diabetes mellitus ratio (p = 0.04), hypertension (p = 0.24), cardiovascular (p = 0.8), smoker (p = 0.63), and ex-smoker (p = 0.3).Conclusion Li-ESWT have a potential long-term efficacy on different degrees of ED evidenced by the improvement in the penile hemodynamics at the final follow-up particularly in those with controlled diabetes mellitus and advancing age.

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Elshorbagy, G., Elsayed, A., ElGhoniemy, M., Rassol, M., Elkousy, M., Gharably, M. (2023). The Efficacy of Low-Intensity Shock Wave Therapy based on the Stratification of Erectile Dysfunction Patients: A Long-term Follow-up. https://doi.org/10.21203/rs.3.rs-3338668/v1

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Auteur(s)

Galal Elshorbagy Ahmed S. Elsayed Mohamed ElGhoniemy Mohamed Abd El Rassol Mohamed Magdy Elkousy Mohamed Aboul Fotouh El Gharably

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