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Prevalence of emergence delirium and associated factors among old-age patients who underwent elective surgery in the Teaching Hospitals of Ethiopia, Ethiopia, 2021. A multicenter prospective observational study

Article scientifique 2022 Anglais

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Abstract Background Emergence Delirium is a common and serious post-operative complication in surgical patients, especially in the old-age. It occurs at any time in the perioperative period, during or immediately following emergence from general anesthesia. Unfortunately, it is highly associated with post-operative complications such as decrease in functional capacity, prolonged hospital stay, an increase in health care costs and morbidity and mortality. The goal of this study was to determine the prevalence of emergence delirium and associated factors among old-age patients who underwent elective surgery in the Teaching Hospitals of Ethiopia at post anesthesia care unit, 2021. Methods A multi-center prospective observational study was conducted at the post-anesthetic care unit of four teaching hospitals in Ethiopia. Old-age surgical patients admitted to Post-anesthesia Care Unit who underwent elective surgery in the four Teaching Hospitals of Ethiopia were selected by using simple random sampling. Pretested structured questionnaire was used to collect data. Data were entered in to Epidata (version 4.6) and exported to the SPSS (version 25.0). Binary logistic regression was used to identify factors independently associated with emergence delirium. Results Out of 384 old-age patients included in the study with 100% response rate, the Prevalence of emergence delirium was 27.6%. Preoperative low hemoglobin levels (AOR: 2.0, 95%CI; 1.77–3.46), opioids (AOR: 8.0, 95%CI; 3.22–27.8) and anti-cholinergic premedications (AOR: 8.5, 95%CI; 6.85–17.35), and post-operative pain (AOR: 3.10, 95CI; 2.07–9.84) at PACU were independently associated with emergence delirium. Conclusion The Prevalence of emergence delirium was high. Old-age patients who were premedicated with anti-cholinergic and opioids, those patients who had low pre-operative hemoglobin and post-operative pain were independently associated with emergence delirium. Adequate pre-operative optimization and post-operative analgesia may reduce the Prevalence of emergence delirium.

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Tageza, T. (2022). Prevalence of emergence delirium and associated factors among old-age patients who underwent elective surgery in the Teaching Hospitals of Ethiopia, Ethiopia, 2021. A multicenter prospective observational study. https://doi.org/10.21203/rs.3.rs-1719192/v1

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