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General characteristics and familial aggregation in patients with systemic lupus erythematosus

Article scientifique 2018 Anglais

Résumé

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the production of autoantibodies, which deposit within tissues and fix complement leading to systemic inflammation (1). Is a heterogeneous disease with a continuum of disease activity. Some patients can have predominant skin and joint involvement, whereas others can present with organ-threatening diseases such as nephritis, cardiac involvement or even neurologic manifestations. Relatives of patients with SLE appear to be at higher risk of SLE and other autoimmune diseases, but estimates of individual familial risks are largely unavailable or unreliable (2,3).

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Dună, M., Predețeanu, D., Berghea, F., Abobului, M., Vlad, V., Bălănescu, A., Opriș-Belinski, D., Borangiu, A., Groşeanu, L., Săulescu, I., Negru, M., Daia, S., Mazilu, D., Ionescu, R. (2018). General characteristics and familial aggregation in patients with systemic lupus erythematosus. https://doi.org/10.37897/rjr.2018.3.5

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Auteur(s)

Mădălina-Puşa Dună Denisa Predețeanu Florian Berghea M. Abobului Violeta Vlad Andra Bălănescu Daniela Opriș-Belinski A. Borangiu L. Groşeanu I. Săulescu Maria-Magdalena Negru Sânziana Daia Diana Mazilu Ruxandra Ionescu

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