Seroprevalence of Syphilis, HBV and Its Associated Risk Factors Among Pregnant Women Attending at Saint Paul’s Hospital Millennium Medical College, Addis Ababa Ethiopia

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Abstract Background: Syphilis and Hepatitis B Virus (HBV) share similar modes of transmission. Their occurrence during pregnancy has an adverse effect both on the fetus and pregnant women. The aim of this study was to determine the seroprevalence and associated risk factors of syphilis and HBV among pregnant women. Methods: A cross-sectional study was undertaken from July to September 2019 in 290 pregnant women at Saint Paul’s Hospital Millennium Medical College, Addis Ababa, Ethiopia. Gestational and socioeconomic data were collected using a questionnaire. Chromatographic kits were used to detect the presence of Hepatitis B surface antigen (HBsAg) and antibody against syphilis infection from the serum of study participants. Data were analyzed by SPSS version 22. Bivariate and multivariable analysis was employed to identify factors associated with seroprevalence of syphilis and HBV. Variables with a p-value of < 0.05 were considered as cut point to determine a significant association. Results: Seroprevalence of HBV and syphilis infection were found to be 4.5% and 2.4 % respectively. Having multiple sexual partner [AOR=3.99, 95%Cl= 1.20-13.38, p=0.025] was significantly associated with HBV infection. Conclusion: In the study the seroprevalence of HBV and syphilis is moderate; having multiple sexual partners was found to be significantly associated with the prevalence of HBV infection.

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